The Science behind Healthy Metal Magnesium Glycinate
Magnesium Deficiency is a silent health epidemic.
Over 60% of us suffer and the implications are significant from endangering heart health, chronic stress, osteoporosis to diabetes.
The body cannot produce it’s own magnesium so we have to find it from external sources like food or minerals.
Industrial agricultural has been detrimental to our modern diets as the process and chemicals have caused an 80% drop in vegetable mineral content.
Lets dig in
Agricultural Impact
Industrial agricultural has been detrimental to our modern diets as the process, chemicals and unnatural demands from the earth have leeched the soil of vital minerals leaving the our food depleted of the nutrients our body needs by the time it reaches us.
A staggering 80% drop in vegetable magnesium content over the last century has turned this nutrient deficiency into a silent epidemic.
So how does it work?
Magnesium Glycinate plays a crucial role in over 300 biochemical processes in the body.
Lets break them down:
Bone Health
About 60% of the body's magnesium is stored in the bones, where it plays a role in bone formation and maintenance.
Magnesium influences the activities of osteoblasts and osteoclasts, the cells responsible for bone formation and resorption, respectively. It also helps regulate calcium levels, which are critical for bone density.
And we did our homework too.
Check out the references below:
Enzyme Activation and Energy Production: "Magnesium in Man: Implications for Health and Disease" - Physiological Reviews. This review discusses magnesium's role as a cofactor for over 300 enzymes, its involvement in ATP synthesis, and its necessity for DNA and RNA synthesis.
Romani, A. M. P. (2011). Magnesium in health and disease. Metallomics, 3(6), 490–498. doi:10.1039/c0mt00093b.
Muscle Function and Nervous System Regulation:
"Magnesium in Health and Disease" - Nutrients. This article explores magnesium's role in muscle contraction, relaxation, and its effects on the nervous system.
Reddy, S. T., & O'Neill, E. (2017). Magnesium, an essential electrolyte: Clinical implications and evidence-based supplementation options. Journal of Clinical Medicine, 6(12), 68. doi:10.3390/jcm6120068.
Bone Health:
"Magnesium and bone health: A systematic review" - Nutrients. This review highlights magnesium's role in bone structure and density, discussing its interaction with calcium and its impact on osteoblast and osteoclast activity.
Rude, R. K., Gruber, H. E., Wei, L. Y., Frausto, A., & Mills, B. G. (2006). Magnesium deficiency: Effect on bone and mineral metabolism in the mouse. Calcified Tissue International, 79(4), 255–261. doi:10.1007/s00223-006-0018-7.
Cardiovascular Health:
"Magnesium and cardiovascular disease: A review" - American Journal of Cardiology. This paper examines the role of magnesium in blood pressure regulation, heart rhythm, and prevention of heart disease.
Zeng, C., Li, H., Wei, J., Yang, T., Deng, Z. H., Yang, Y., ... & Lei, G. H. (2015). Association between dietary magnesium intake and C-reactive protein levels in the US adult population. Journal of Human Hypertension, 29(8), 436–441. doi:10.1038/jhh.2015.4.
Insulin Sensitivity and Blood Sugar Control:
"Magnesium and the metabolic syndrome" - Diabetes Care. This article explores the link between magnesium, insulin sensitivity, and type 2 diabetes.
Guerrero-Romero, F., & Rodríguez-Morán, M. (2006). Low serum magnesium levels and metabolic syndrome. Acta Diabetologica, 43(2), 71–77. doi:10.1007/s00592-006-0204-z.
Antioxidant Defense and Mental Health:
"Magnesium, oxidative stress, and inflammation: An integrative and practical perspective" - Journal of the American College of Nutrition. This paper reviews magnesium's role in reducing oxidative stress and inflammation, and its potential effects on mental health.
Barbagallo, M., & Dominguez, L. J. (2010). Magnesium and aging. Current Pharmaceutical Design, 16(7), 832–839. doi:10.2174/138161210790883673.
General reading:
Schuette, S. A., et al. (1994). "Comparative absorption of magnesium salts." Pharmaceutical Research, 11(5), 676-682.
Firoz, M., & Graber, M. (2001). "Bioavailability of US commercial magnesium preparations." Magnesium Research, 14(4), 257-262.
Abbasi, B., et al. (2012). "The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial." Journal of Research in Medical Sciences, 17(12), 1161-1169.
Wienecke, T., & Hansen, J. M. (2020). "Magnesium deficiency and sleep: The evidence." Journal of Clinical Sleep Medicine, 16(3), 341-344.
Dahle, L. O., et al. (1995). "The effect of oral magnesium substitution on pregnancy-induced leg cramps." American Journal of Obstetrics and Gynecology, 173(1), 175-180.
Boyle, N. B., et al. (2017). "The effects of magnesium supplementation on subjective anxiety and stress—a systematic review." Nutrients, 9(5), 429.
Walker, A. F., et al. (2003). "Magnesium supplementation: Effects on physical performance and clinical studies." Magnesium Research, 16(3), 183-191.
Kass, L., et al. (2012). "Effect of magnesium supplementation on blood pressure: A meta-analysis." European Journal of Clinical Nutrition, 66(4), 411-418.
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